Feasibility of transdermal ethanol sensing for the detection of intoxicated drivers.

Gregory D Webster, Hampton C Gabler
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Abstract

Transdermal ethanol detection is a promising method that could prevent drunk driving if integrated into an ignition interlock system. However, experimental data from previous research has shown significant time delays between alcohol ingestion and detection at the skin which makes real time estimation of blood alcohol concentration via skin measurement difficult. Using a validated model we studied the effects that body weight, metabolic rate and ethanol dose had on the time lag between the blood alcohol concentration and transdermal alcohol concentration. The dose of alcohol ingested was found to have the most significant effect on the skin alcohol lag time; a dose of 15 ml of ethanol resulted in a peak lag time of approximately 33 minutes, while a dose of 60 ml of ethanol resulted in a peak time lag of 53 minutes. The time lag was found to be insensitive to body mass and only moderately sensitive to changes in metabolic rates.

经皮乙醇传感检测醉酒驾驶员的可行性。
透皮乙醇检测是一种很有前途的方法,可以防止酒后驾驶,如果集成到点火联锁系统。然而,先前研究的实验数据表明,酒精摄入和皮肤检测之间存在明显的时间延迟,这使得通过皮肤测量实时估计血液酒精浓度变得困难。采用验证模型研究了体重、代谢率和乙醇剂量对血液酒精浓度和透皮酒精浓度时间差的影响。酒精摄入剂量对皮肤酒精滞后时间的影响最为显著;15毫升乙醇的剂量导致大约33分钟的峰值滞后时间,而60毫升乙醇的剂量导致53分钟的峰值滞后时间。发现时间滞后对体重不敏感,对代谢率的变化仅中等敏感。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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