Peculiarities of coronary artery atherosclerosis in male patients of Yakut nationality with ischemic heart disease.

Abstract

Purpose: To study the peculiarities of coronary artery atherosclerosis according to data of selective coronaroangiography (SCAG) in male patients of Yakut nationality with ischemic heart disease (IHD).

Materials and methods: 148 Yakut and Russian males with IHD have been observed in the research. They were inpatients of a cardiology unit, Republican Hospital No.1--National Centre of Medicine, Yakutsk for 2004-2006. Patients were divided into two clinical Groups: 1--Yakut males with IHD (n = 74, mean age 53.8 +/- 09 years); 2--Russian males with IHD (n = 74, mean age 52.9 +/- 0.9 years). The study was based on anamnesis data, clinical investigation and included data of twofold measure of blood pressure, anthropometry, electrocardiography, echocardiography, SCAG, determination of levels of total cholesterol (TCh) and cholesterol of high- (HDL) and low-density (LDL) lipoproteins and triglycerides (TG).

Results: The Yakuts have more frequently 1-vascular lesion of CA according to SCAG. The frequency of lesion left anterior descending artery (LAD) and right coronary artery (RCA) is equal in both groups, at the same time occlusion of LAD more frequently occurred in Group 1 (61% against 42%), and occlusion of RCA more often occurred in Group 2 (46% against 21%).

Conclusion: Atherosclerosis of CA among Yakut patients with IHD is less expressed. Risk factors (RF) among Yakuts with IHD, like smoking, overweight, lipid disorders occurred less frequently than in group of non-Natives.