Biorhythmological and clinico-functional features of arterial hypertension under geoecological conditions of the North.

Abstract

Study design: A group of the examined patients with arterial hypertension comprised 412 persons, living under the conditions of the North and the moderate latitudes. 24-hour monitoring of blood pressure (BP) and echocardiography were used. Routine heliogeophysical monitoring was conducted. Heliogeophysical situation at early ontogenesis of the examined was evaluated. Testing magnetic and hypogeomagnetic impacts were used.

Results: A considerable disorder of the circadian rhythms of hemodynamics manifesting as insufficient decrease of BP at night was revealed in a subgroup of the patients with arterial hypertention living in the North. Using a multifactor analysis, the heliogeophysical patterns of early ontogenesis were revealed in subgroups of the examined with high indices of variability, disorders of the circadian rhythms of BP. A diagnostic test using echocardiography and testing impact by a constant magnetic field was developed to evaluate the hemodynamic reaction to changes of the heliogeophysical environment. While studying the impact of hypogeomagnetic environment on some functional features of the cardiovascular system in the subgroup of patients, it was found that geomagnetic screening caused decrease of systolic arterial pressure, more expressed in "nondippers".

Conclusion: Thus, some hemodynamic mechanisms of coupling the time organization of cardiovascular system with periodical heliogeophysical variations developed during ontogenesis were defined.