Depression and risk of cardiovascular diseases among males aged 25-64 (WHO MONICA--psychosocial).

Alaska medicine Pub Date : 2007-01-01
H A Gromova, V V Gafarov, I V Gagulin
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Abstract

Objective: To study the influence of depression on risk of cardiovascular diseases development during 10 years in non-organized male population aged 25-64.

Study design and methods: Within the framework of the MONICA--psychosocial program a representative sample of 657 men 25-64 years old (1994 year) was examined. Depression was measured at baseline with the use of the MONICA--psychosocial Interview Depression scale. The incidence of new cases of AH, MI and stroke was revealed in the WHO "Registry MI" and "Registry stroke" 10-year follow-up. Cox is a proportional regression model that was used for estimation of RR.

Results: The proportion of depression in the cohort of men with AH was 28.9%, with MI--65.8% and of men with stroke 70.6%. The relative risk of development of AH, MI, stroke during the first five years of supervision in a group with the high level of depression as compared to those in whom depression was not observed was 6.7 times (p < 0.01), 2.26 times (p < 0.05), 6.4 times higher (p < 0.01), respectively. Within 10 years, the risk of development of cardiovascular diseases in men with high level of depression was: for AH--RR = 4.2; for MI--RR = 2.4; and stroke--RR = 5.2 (p < 0.05 comparing to those without it.

Conclusion: Depression is a predictor of cardiovascular diseases in middle-aged men.

25-64岁男性抑郁症和心血管疾病风险(世卫组织MONICA——心理社会)。
目的:研究25 ~ 64岁无组织男性人群10年间抑郁对心血管疾病发生风险的影响。研究设计和方法:在MONICA-社会心理项目的框架内,对657名25-64岁(1994年)男性的代表性样本进行了检查。抑郁在基线时使用MONICA——心理社会访谈抑郁量表进行测量。世卫组织“心肌梗死登记”和“脑卒中登记”10年随访中揭示了AH、心肌梗死和脑卒中新发病例的发生率。Cox是一个用于估计RR的比例回归模型。结果:AH男性队列中抑郁症的比例为28.9%,MI为65.8%,卒中男性为70.6%。抑郁程度高组监测前5年发生AH、MI、卒中的相对危险度分别为未抑郁组的6.7倍(p < 0.01)、2.26倍(p < 0.05)、6.4倍(p < 0.01)。在10年内,高抑郁水平男性患心血管疾病的风险为:AH- RR = 4.2;对于MI—RR = 2.4;卒中——RR = 5.2 (p < 0.05)。结论:抑郁是中年男性心血管疾病的预测因子。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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