Cranial base fracture and rhino cerebrospinmal fluid leakage. A case report.

G Magliulo, A Celebrini, G Cuiuli, D Parlotto
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Abstract

Oto cerebrospinal fluid leakage occurs frequently in skull base fractures but it is not always recognized which may produce potentially serious consequences on the prognosis. The aim of this study is to present a case of an extended skull base fracture with bad defined symptoms. A male in coma was admitted to our hospital following a road accident. Imaging revealed a fracture that transversally crossed the squamous occipital bone and petrous portions of temporal bone on the right, the sphenoid bone, and the left zygomatic bone. Ten days later the patient regained consciousness presenting symptoms of right complete hearing loss, cephalalgia and fever. Lumbar puncture showed a Gram negative germ growth. After specific antibiotic treatment he underwent surgery with exclusion of the middle ear and the mastoid from outside by obliterating the Eustachian tube, sealing the surgical cavity (subtotal petrosectomy) with abdominal fat and closing the external auditory canal as a blind sac. At the same time, nasal fibroendoscopy was also performed to close the fistulas in the sphenoid region. Since the cephalalgia persisted further CT examination was performed and revealed another fracture rima in the ethmoid bone. Nasal fibroendoscopy was performed again to close this fistula. The symptoms thus disappeared and the patient has continued to be symptom-free during the two years follow-up. Skull base fractures may involve various bone structure (petrous portion of temporal bone, ethmoid, sphenoid, parietal bone). As a result of the complex anatomy of the skull base, the fracture may damage numerous vital structures (cranial nerves, internal carotid artery, cavernous sinus, jugular vein etc) and the dura mater, causing cerebrospinal fluid leak. When the fracture in the petrous bone is transversal, it is highly important not to delay surgery. In fact the otic capsule does not repair but the bone step is covered by a thin layer of fibrous tissue. For this reason patients, with clear damage to the otic capsule, risk meningitis. Fistulas in the ethmoid are the most difficult to diagnose and the easiest to underestimate. It is fundamental to follow the appropriate diagnostic procedure.

颅底骨折及犀牛脑脊液漏。一份病例报告。
脑脊液漏常发生在颅底骨折中,但并不总是被认识到,这可能对预后产生潜在的严重后果。本研究的目的是提出一个病例的扩展颅底骨折与不良定义的症状。一名昏迷的男性因交通事故被送往我院。影像学显示骨折横贯鳞状枕骨和右侧颞骨的岩状部分、蝶骨和左侧颧骨。10天后患者恢复意识,表现为右侧完全失聪、头痛和发热。腰椎穿刺显示革兰氏阴性细菌生长。经过特殊的抗生素治疗后,他接受了手术,通过切除咽鼓管,用腹部脂肪封闭手术腔(次全石油切开术)并关闭外耳道作为盲囊,从外部排除中耳和乳突。同时行鼻纤维内镜关闭蝶窦区瘘管。由于头痛持续存在,进行了进一步的CT检查,发现在筛骨另一处骨折。再次行鼻纤维内窥镜检查以关闭该瘘。因此,症状消失,患者在两年随访期间持续无症状。颅底骨折可累及多种骨结构(颞骨岩部、筛骨、蝶骨、顶骨)。由于颅底复杂的解剖结构,骨折可损伤许多重要结构(颅神经、颈内动脉、海绵窦、颈静脉等)和硬脑膜,引起脑脊液漏。当岩质骨的骨折是横向的,不延误手术是非常重要的。事实上,耳囊不能修复,但骨台阶被一层薄薄的纤维组织覆盖。因此,有明显耳膜损伤的患者有患脑膜炎的危险。筛瘘管是最难诊断的,也是最容易被低估的。遵循适当的诊断程序是至关重要的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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