[Expression of BDNF and trk B in the cochleas of the aged rats].

Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology Pub Date : 2006-10-01

Yuru Li, Delong Liu, Yuanyuan Zhang, Ping Wang, Baodong Du

引用次数: 0

Abstract

Objective: To explore the correlation between the expression of brain derived neurotrophic factor (BDNF) and presbycusis in the cochleae of the aged rats.

Method: The mRNA expression of BDNF and presbycusis in the cochleas of the aged rats was quantitated by real time PCR.

Result: The expression of BDNF in the cochleas of the aged rats with presbycusis was obviously less than that in the control group. And the difference was statistically significant.

Conclusion: The expression of BDNF is closely correlated to presbycusis in the aged rats.

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老年大鼠耳蜗BDNF和trk B的表达。

目的:探讨老年大鼠耳蜗脑源性神经营养因子(BDNF)表达与老年性耳聋的关系。方法:采用实时荧光定量PCR法测定老龄大鼠耳蜗BDNF mRNA表达和老年性耳蜗组织的变化。结果:老年老年性耳聋大鼠耳蜗中BDNF表达明显低于对照组。这一差异在统计学上是显著的。结论:BDNF的表达与老年大鼠老年性痴呆密切相关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology

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