[Adenoid cystic carcinoma of ENT associated with hard lump: a report of 9 cases].

Leiji Li, Wenlong Luo, Xiuni Gan, Lisha Su, Weidong Zeng
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Abstract

Objective: To assess the clinical and pathological features of the patients with ENT adenoid cystic carcinoma (ENTACC) who presented with hard lump, and to detect its prognosis.

Method: A retrospective analysis was performed on 9 patients with ENTACC by their clinical data.

Result: The period from the occurrence of primary symptoms to definite diagnosis was 4 years and 3 months on average. All patients were followed up from 6 months to 15 years. All of the cases relapsed after operation and radiotherapy. Five patients died, among which 3 died with lung metastases, 2 with local lymphatic metastases, 1 with bone metastases and 1 with encephalic diffusion. The other 4 cases still survive. The longest survival period with tumor was 6 years and 3 months.

Conclusion: The pathological result of these 9 cases were all salivary gland derived adenoid cystic carcinoma of solid type. It was mainly characterized by the development of ENT hard lump. All of the patients should be diagnosed in time. Extensive excision and postoperative radiotherapy are needed at the first time. The tumor of solid histological pattern appears with much poorer prognosis compared with that of other histological pattern.

耳鼻喉腺样囊性癌合并硬块附9例报告
目的:探讨耳鼻喉腺样囊性癌(ENTACC)伴硬块的临床及病理特点,探讨其预后。方法:对9例ENTACC患者的临床资料进行回顾性分析。结果:从首发症状出现到确诊平均时间为4年3个月。所有患者随访6个月至15年。所有病例经手术及放疗后均复发。死亡5例,其中肺转移3例,局部淋巴转移2例,骨转移1例,脑扩散1例。其余4例仍存活。肿瘤患者的最长生存期为6年3个月。结论:9例患者病理结果均为实体型唾液腺源性腺样囊性癌。主要表现为耳鼻喉硬块的形成。所有的病人都应该得到及时的诊断。第一次需要广泛切除和术后放疗。实性组织型肿瘤预后较其他组织型差。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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