Sequencing of a novel HLA-A allele, A*6836, showing a Bw4 epitope.

A Balas, F García-Sánchez, J L Vicario
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引用次数: 9

Abstract

A novel A*6836 allele was completely characterized by sequence-based typing (SBT) in a cord blood sample from an Ecuadorian donor. A*6836 discloses six clustered amino acid residue changes at the alpha-1 domain, codons 76-83, regarding its closer A*680102 allele. Therefore, A*6836 would be a new human leukocyte antigen (HLA)-A molecule showing a Bw4-epitope.

新的HLA-A等位基因a *6836的测序,显示一个Bw4表位。
一种新的A*6836等位基因通过序列分型(SBT)在厄瓜多尔供体脐带血样本中被完全鉴定。A*6836在A*680102等位基因的α -1结构域密码子76 ~ 83处披露了6个簇状氨基酸残基变化。因此,A*6836可能是一个具有bw4表位的新的人白细胞抗原(HLA)-A分子。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Tissue antigens
Tissue antigens 医学-病理学
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