Complications of HIV disease and antiretroviral therapy.

Diane V Havlir, Judith S Currier
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Abstract

As antiretroviral treatment regimens become more potent and easier to administer, differences in the rates of adverse events and complications associated with treatment will increasingly drive decisions regarding the selection of therapy. This year's Conference on Retroviruses and Opportunistic Infections featured a wide range of research directed toward understanding the pathogenesis, treatment, and long-term consequences of complications associated with HIV infection and the use of antiretroviral therapy in both resource-limited settings and in the developed world. This review will summarize information on complications of antiretroviral therapy in resource-limited settings, hepatitis C virus, tuberculosis, and discussion of metabolic, cardiovascular, and renal complications.

艾滋病毒疾病并发症和抗逆转录病毒治疗。
随着抗逆转录病毒治疗方案变得更有效和更容易实施,与治疗相关的不良事件和并发症发生率的差异将日益推动有关治疗选择的决定。今年的逆转录病毒和机会性感染会议以广泛的研究为特色,旨在了解与艾滋病毒感染相关的并发症的发病机制、治疗和长期后果,以及在资源有限的环境和发达国家使用抗逆转录病毒治疗。这篇综述将总结在资源有限的情况下抗逆转录病毒治疗的并发症、丙型肝炎病毒、结核病的信息,并讨论代谢、心血管和肾脏并发症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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