Developments in antiviral drug design, discovery and development in 2004.

Nicholas A Meanwell, Makonen Belema, David J Carini, Stanley V D'Andrea, John F Kadow, Mark Krystal, B Narasimhulu Naidu, Alicia Regueiro-Ren, Paul M Scola, Sing-Yuen Sit, Michael A Walker, Tao Wang, Kap-Sun Yeung
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引用次数: 5

Abstract

This article summarizes key aspects of progress made during 2004 toward the design, discovery and development of antiviral agents for clinical use. Important developments in the identification, characterization and clinical utility of inhibitors of human immunodeficiency virus; the hepatitis viruses, hepatitis B, hepatitis C; the herpes family of viruses, herpes simplex viruses 1 and 2, varicella zoster virus, Epstein-Barr virus and human cytomegalovirus; the respiratory viruses, influenza, respiratory syncytial virus, human metapneumovirus, picornaviruses, measles and the severe acute respiratory syndrome coronavirus; human papilloma virus; rotavirus; Ebola virus and West Nile virus, are reviewed.

2004年抗病毒药物的设计、发现和开发进展。
本文综述了2004年在临床使用抗病毒药物的设计、发现和开发方面取得的主要进展。人类免疫缺陷病毒抑制剂的鉴定、表征和临床应用的重要进展;肝炎病毒,乙型肝炎,丙型肝炎;疱疹病毒家族、单纯疱疹病毒1型和2型、水痘带状疱疹病毒、eb病毒和人巨细胞病毒;呼吸道病毒、流感、呼吸道合胞病毒、人偏肺病毒、小核糖核酸病毒、麻疹和严重急性呼吸道综合征冠状病毒;人乳头瘤病毒;轮状病毒;对埃博拉病毒和西尼罗河病毒进行了综述。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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