Amplitude-Integrated Electroencephalography: A Tool for Monitoring Silent Seizures in Neonates

IF 3.2 3区医学 Q2 CLINICAL NEUROLOGY

Pediatric neurology Pub Date : 2006-03-01 DOI:10.1016/j.pediatrneurol.2005.06.018

Eilon Shany MD, Sonia Khvatskin MD, Agneta Golan MD, Michael Karplus MD

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引用次数: 28

Abstract

The clinical use of amplitude-integrated electroencephalography in the diagnosis of seizures in high-risk newborn infants with suspected central nervous system insult is evaluated with emphasis on silent seizures. Recordings from 93 infants with suspected central nervous system insults over a period of 7 years were retrospectively analyzed for the presence of electrical seizures and for their correlation with clinical events. Thirty infants (32%) had overt clinical seizures; 29 (97%) of these manifested clear seizure patterns in their tracings, and the remaining one infant had a suspected tracing. Eleven infants (12%) had subtle clinical seizures; of these 7 (59%) had clear electrical seizures, 3 (31%) had suspected tracing, and one had a normal tracing. Fifty-two infants (56%) had no clinical events indicative of seizures; of these 8 (15%) had clear electrical seizures, 17 (33%) had suspected tracings, and 27 (52%) had normal tracings. Electroencephalographic seizures are common in sick newborn infants. Amplitude-integrated electroencephalography can provide important information concerning their neurologic status and help to confirm or refute the presence of seizures in clinically suspected cases and detect infants with silent seizures.

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波幅综合脑电图:监测新生儿无症状癫痫发作的工具

临床应用波幅综合脑电图诊断癫痫发作在高危新生儿怀疑中枢神经系统损伤评估，重点是无声癫痫发作。回顾性分析了7年间93例疑似中枢神经系统损伤的婴儿的记录，分析了电性癫痫发作的存在及其与临床事件的相关性。30名婴儿(32%)有明显的临床癫痫发作;其中29例(97%)患儿在追踪中表现出明显的癫痫发作模式，其余1例患儿疑似有追踪。11名婴儿(12%)有轻微的临床癫痫发作;其中7例(59%)有明显的电性癫痫发作，3例(31%)有可疑的追踪，1例有正常的追踪。52名婴儿(56%)没有癫痫发作的临床事件;其中8例(15%)有明显的电性癫痫发作，17例(33%)有可疑的示踪，27例(52%)示踪正常。脑电图发作在生病的新生儿中很常见。波幅综合脑电图可以提供有关其神经系统状态的重要信息，有助于证实或驳斥临床怀疑病例中癫痫的存在，并有助于发现无症状癫痫发作的婴儿。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Pediatric neurology 医学-临床神经学

CiteScore

4.80

自引率

2.60%

发文量

176

审稿时长

78 days

期刊介绍： Pediatric Neurology publishes timely peer-reviewed clinical and research articles covering all aspects of the developing nervous system. Pediatric Neurology features up-to-the-minute publication of the latest advances in the diagnosis, management, and treatment of pediatric neurologic disorders. The journal''s editor, E. Steve Roach, in conjunction with the team of Associate Editors, heads an internationally recognized editorial board, ensuring the most authoritative and extensive coverage of the field. Among the topics covered are: epilepsy, mitochondrial diseases, congenital malformations, chromosomopathies, peripheral neuropathies, perinatal and childhood stroke, cerebral palsy, as well as other diseases affecting the developing nervous system.