SARS-COV-2 ANTIBODY PREVALENCE AMONG HEALTHCARE WORKERS AND FIRST RESPONDERS, FLORIDA, MAY-JUNE 2020.

Florida public health review Pub Date : 2021-02-25
James Matthias, Emma C Spencer, Mara Michniewicz, Thomas M Bendle, Craig Wilson, Kenneth A Scheppke, Carina Blackmore, Aaron Otis, Scott A Rivkees
{"title":"SARS-COV-2 ANTIBODY PREVALENCE AMONG HEALTHCARE WORKERS AND FIRST RESPONDERS, FLORIDA, MAY-JUNE 2020.","authors":"James Matthias, Emma C Spencer, Mara Michniewicz, Thomas M Bendle, Craig Wilson, Kenneth A Scheppke, Carina Blackmore, Aaron Otis, Scott A Rivkees","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>The SARS-CoV-2 virus responsible for severe respiratory infection associated with coronavirus disease 2019 (COVID-19) was first confirmed in Florida on March 1, 2020. Responding to the pandemic, multi-agency collaborative partnerships put in place actions integrating point-of-care antibody testing at established large-scale COVID-19 testing sites where the baseline seropositivity of COVID-19 in health care workers and first responders in Florida at the start of the pandemic was established.</p><p><strong>Purpose: </strong>Determine the seropositivity of healthcare workers and first responders at five drive thru testing sites using a rapid SARS-CoV-2 antibody test in Florida from May 6 through June 3, 2020.</p><p><strong>Methods: </strong>The first drive-thru SARS-CoV-2 antibody test site was opened at Miami Hard Rock Stadium, May 6, 2020. Testing expanded to three additional sites on May 9, 2020: Jacksonville, Orlando, and Palm Beach. The fifth and final site, Miami Beach, began testing on May 21, 2020. Healthcare workers and first responder's self-seeking SARS-CoV-2 testing were designated for antibody testing and completed a laboratory collection form onsite for the point-of-care test. All testing was performed on whole blood specimens (obtained by venipuncture) using the Cellex Inc. qSARS-CoV-2 IgG/IgM Rapid Test. Seropositivity was assessed by univariate analysis and by logistic regression including the covariates age, sex, race/ethnicity, and testing location.</p><p><strong>Results and discussion: </strong>As of June 3, 2020, of 5,779 healthcare workers and first responders tested, 4.1% were seropositive (range 2.6-8.2%). SARS-COV-2 antibody tests had higher odds of being positive for persons testing at the Miami Hard Rock Stadium (aOR 2.24 [95% C.I. 1.48-3.39]), persons of Haitian/Creole ethnicity (aOR 3.28 [95% C.I. 1.23-8.72]), Hispanic/Latino(a) ethnicity (aOR 2.17 [95% C.I. 1.50-3.13], and Black non-Hispanic persons (aOR 1.63 [95% C.I. 1.08-2.46]). SARS-COV-2 antibody prevalence among first responders and healthcare workers in five sites in Florida varied by race and ethnicity and by testing location.</p>","PeriodicalId":73034,"journal":{"name":"Florida public health review","volume":"18 1","pages":"1-10"},"PeriodicalIF":0.0000,"publicationDate":"2021-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040388/pdf/nihms-1684634.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Florida public health review","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

Background: The SARS-CoV-2 virus responsible for severe respiratory infection associated with coronavirus disease 2019 (COVID-19) was first confirmed in Florida on March 1, 2020. Responding to the pandemic, multi-agency collaborative partnerships put in place actions integrating point-of-care antibody testing at established large-scale COVID-19 testing sites where the baseline seropositivity of COVID-19 in health care workers and first responders in Florida at the start of the pandemic was established.

Purpose: Determine the seropositivity of healthcare workers and first responders at five drive thru testing sites using a rapid SARS-CoV-2 antibody test in Florida from May 6 through June 3, 2020.

Methods: The first drive-thru SARS-CoV-2 antibody test site was opened at Miami Hard Rock Stadium, May 6, 2020. Testing expanded to three additional sites on May 9, 2020: Jacksonville, Orlando, and Palm Beach. The fifth and final site, Miami Beach, began testing on May 21, 2020. Healthcare workers and first responder's self-seeking SARS-CoV-2 testing were designated for antibody testing and completed a laboratory collection form onsite for the point-of-care test. All testing was performed on whole blood specimens (obtained by venipuncture) using the Cellex Inc. qSARS-CoV-2 IgG/IgM Rapid Test. Seropositivity was assessed by univariate analysis and by logistic regression including the covariates age, sex, race/ethnicity, and testing location.

Results and discussion: As of June 3, 2020, of 5,779 healthcare workers and first responders tested, 4.1% were seropositive (range 2.6-8.2%). SARS-COV-2 antibody tests had higher odds of being positive for persons testing at the Miami Hard Rock Stadium (aOR 2.24 [95% C.I. 1.48-3.39]), persons of Haitian/Creole ethnicity (aOR 3.28 [95% C.I. 1.23-8.72]), Hispanic/Latino(a) ethnicity (aOR 2.17 [95% C.I. 1.50-3.13], and Black non-Hispanic persons (aOR 1.63 [95% C.I. 1.08-2.46]). SARS-COV-2 antibody prevalence among first responders and healthcare workers in five sites in Florida varied by race and ethnicity and by testing location.

2020 年 5 月至 6 月佛罗里达州医护人员和急救人员的 SARS-COV-2 抗体流行率。
背景:2020 年 3 月 1 日,佛罗里达州首次确诊了与 2019 年冠状病毒病相关的严重呼吸道感染(COVID-19)的 SARS-CoV-2 病毒。为了应对这次大流行,多机构协作伙伴关系采取了一些行动,在已建立的大规模 COVID-19 检测点进行护理点抗体检测,并在大流行开始时确定了佛罗里达州医护人员和急救人员的 COVID-19 血清阳性率基线。目的:从 2020 年 5 月 6 日至 6 月 3 日,在佛罗里达州使用快速 SARS-CoV-2 抗体检测法确定五个驾车直达检测点医护人员和急救人员的血清阳性率:方法:2020 年 5 月 6 日,在迈阿密硬石体育场(Miami Hard Rock Stadium)开设了第一个汽车直通式 SARS-CoV-2 抗体检测点。2020 年 5 月 9 日,测试扩展到另外三个地点:杰克逊维尔、奥兰多和棕榈滩。第五个也是最后一个测试点迈阿密海滩于 2020 年 5 月 21 日开始测试。医护人员和急救人员自行寻求进行 SARS-CoV-2 检测,他们被指定进行抗体检测,并在现场填写实验室采集表,以进行床旁检测。所有检测均使用 Cellex 公司的 qSARS-CoV-2 IgG/IgM 快速检测仪对全血标本(通过静脉穿刺获得)进行。血清阳性率通过单变量分析和逻辑回归(包括年龄、性别、种族/民族和检测地点等协变量)进行评估:截至 2020 年 6 月 3 日,在接受检测的 5779 名医护人员和急救人员中,4.1% 的人血清呈阳性(范围为 2.6-8.2%)。在迈阿密硬石体育场接受检测的人员(aOR 2.24 [95% C.I. 1.48-3.39])、海地人/克里奥尔人(aOR 3.28[95%C.I.1.23-8.72])、西班牙裔/拉美裔(a) (aOR 2.17 [95% C.I. 1.50-3.13])和非西班牙裔黑人 (aOR 1.63 [95% C.I. 1.08-2.46])。佛罗里达州五个地点的急救人员和医护人员的 SARS-COV-2 抗体流行率因种族、民族和检测地点而异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信