{"title":"Capturing pathogenic immune cells before they home to brain.","authors":"Lawrence Steinman","doi":"10.1016/j.medj.2021.02.005","DOIUrl":null,"url":null,"abstract":"<p><p>In this issue, Kaufmann and colleagues<sup>1</sup> describe a population of immune cells that home to brain in multiple sclerosis (MS). Using an approved therapeutic, targeting α4β1integrin, they demonstrated how to trap these cells in blood, opening the possibility for their elimination before they cross into brain.</p>","PeriodicalId":272244,"journal":{"name":"Med (New York, N.y.)","volume":" ","pages":"214-216"},"PeriodicalIF":0.0000,"publicationDate":"2021-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.medj.2021.02.005","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Med (New York, N.y.)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/j.medj.2021.02.005","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
In this issue, Kaufmann and colleagues1 describe a population of immune cells that home to brain in multiple sclerosis (MS). Using an approved therapeutic, targeting α4β1integrin, they demonstrated how to trap these cells in blood, opening the possibility for their elimination before they cross into brain.
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