Human Endogenous Natural Products.

Q1 Medicine
Yingjie Bai, Liyun Zhang, Xiaoguang Lei
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引用次数: 0

Abstract

Natural products are a class of chemical compounds that are biosynthesized by living organisms, including humans. Endogenous natural products are produced by human cells as well as by the human microbiome. This contribution describes the current understanding and recent progress made on endogenous natural products that are produced by human cells, including amines, steroids, and fatty acid-derived natural products. The co-metabolism and natural product produced by the human microbiome will also be described, including the involvement of tryptophan, bile acids, choline, and cysteine. New strategies and technologies have been introduced that can be applied to identify and characterize those natural products produced by the human microbiome in terms of their composition and physiological function.

人类内源性天然产物。
天然产物是一类由生物合成的化合物,包括人类。内源性天然产物由人体细胞和人体微生物组产生。这篇文章描述了目前对人类细胞产生的内源性天然产物的理解和最新进展,包括胺、类固醇和脂肪酸衍生的天然产物。还将描述人类微生物组产生的共代谢和天然产物,包括色氨酸、胆汁酸、胆碱和半胱氨酸的参与。新的策略和技术已经被引入,可以用于识别和表征由人类微生物组产生的天然产物的组成和生理功能。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
4.40
自引率
0.00%
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0
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