Optimizing Therapeutic Outcomes With Oral Semaglutide: A Patient-Centered Approach.

Q3 Medicine
Diana M Isaacs, Davida F Kruger, Geralyn R Spollett
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引用次数: 4

Abstract

In September 2019, the U.S. Food and Drug Administration approved oral semaglutide as the first orally administered glucagon-like peptide 1 (GLP-1) receptor agonist for treating people with type 2 diabetes. Although injectable GLP-1 receptor agonists are well-established treatment options for people with type 2 diabetes, clinical experience with an oral formulation in this class is limited. This article provides practical guidance for diabetes care and education specialists on how to effectively counsel patients initiating therapy with oral semaglutide on appropriate administration of the treatment and its possible effects on glycemic control, body weight, and quality of life. Strategies for mitigating potential side effects typical of the GLP-1 receptor agonist class, namely nausea, vomiting, and diarrhea, are also provided. Involving patients in treatment decisions and educating them about available and prescribed medications are key strategies for encouraging treatment adherence and ensuring optimal therapeutic outcomes.

优化口服西马鲁肽的治疗效果:以患者为中心的方法。
2019年9月,美国食品和药物管理局批准口服semaglutide作为治疗2型糖尿病患者的第一种口服胰高血糖素样肽1 (GLP-1)受体激动剂。虽然注射GLP-1受体激动剂是2型糖尿病患者公认的治疗选择,但这类患者口服制剂的临床经验有限。本文为糖尿病护理和教育专家提供了实用的指导,指导他们如何有效地向开始口服西马鲁肽治疗的患者提供适当的治疗建议,以及它对血糖控制、体重和生活质量的可能影响。还提供了减轻GLP-1受体激动剂类典型潜在副作用的策略,即恶心,呕吐和腹泻。让患者参与治疗决策并教育他们了解现有药物和处方药物是鼓励治疗依从性和确保最佳治疗结果的关键策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Diabetes Spectrum
Diabetes Spectrum Medicine-Internal Medicine
CiteScore
2.70
自引率
0.00%
发文量
62
期刊介绍: The mission of Diabetes Spectrum: From Research to Practice is to assist health care professionals in the development of strategies to individualize treatment and diabetes self-management education for improved quality of life and diabetes control. These goals are achieved by presenting review as well as original, peer-reviewed articles on topics in clinical diabetes management, professional and patient education, nutrition, behavioral science and counseling, educational program development, and advocacy. In each issue, the FROM RESEARCH TO PRACTICE section explores, in depth, a diabetes care topic and provides practical application of current research findings.
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