Fereshteh Vajhadin, Mohammad Mazloum-Ardakani, Abbas Amini
{"title":"Metal oxide-based gas sensors for the detection of exhaled breath markers","authors":"Fereshteh Vajhadin, Mohammad Mazloum-Ardakani, Abbas Amini","doi":"10.1002/mds3.10161","DOIUrl":null,"url":null,"abstract":"<p>Exhaled breath test is a typical disease monitoring method for replacing blood and urine samples that may create discomfort for patients. To monitor exhaled breath markers, gas biomedical sensors have undergone rapid progress for non-invasive and point-of-care diagnostic devices. Among gas sensors, metal oxide-based biomedical gas sensors have received remarkable attention owing to their unique properties, such as high sensitivity, simple fabrication, miniaturization, portability and real-time monitoring. Herein, we reviewed the recent advances in chemoresistive metal oxide-based gas sensors with ZnO, SnO<sub>2</sub> and In<sub>2</sub>O<sub>3</sub> as sensing materials for monitoring a range of exhaled breath markers (i.e., NO, H<sub>2</sub>, H<sub>2</sub>S, acetone, isoprene and formaldehyde). We focused on the strategies that improve the sensitivity and selectivity of metal oxide-based gas sensors. The challenges to fabricate a functional gas sensor with high sensing performance along with suggestions are outlined.</p>","PeriodicalId":87324,"journal":{"name":"Medical devices & sensors","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2020-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/mds3.10161","citationCount":"24","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medical devices & sensors","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/mds3.10161","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 24
Abstract
Exhaled breath test is a typical disease monitoring method for replacing blood and urine samples that may create discomfort for patients. To monitor exhaled breath markers, gas biomedical sensors have undergone rapid progress for non-invasive and point-of-care diagnostic devices. Among gas sensors, metal oxide-based biomedical gas sensors have received remarkable attention owing to their unique properties, such as high sensitivity, simple fabrication, miniaturization, portability and real-time monitoring. Herein, we reviewed the recent advances in chemoresistive metal oxide-based gas sensors with ZnO, SnO2 and In2O3 as sensing materials for monitoring a range of exhaled breath markers (i.e., NO, H2, H2S, acetone, isoprene and formaldehyde). We focused on the strategies that improve the sensitivity and selectivity of metal oxide-based gas sensors. The challenges to fabricate a functional gas sensor with high sensing performance along with suggestions are outlined.