Sirius Scheimpflug-Placido versus ultrasound pachymetry for central corneal thickness: meta-analysis.

Eye and vision (London, England) Pub Date : 2021-02-18 DOI:10.1186/s40662-021-00227-5

Yili Jin, Colm McAlinden, Yong Sun, Daizong Wen, Yiran Wang, Jinjin Yu, Ke Feng, Benhao Song, Qinmei Wang, Shihao Chen, Jinhai Huang

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引用次数: 2

Abstract

Background: To compare the difference in central corneal thickness (CCT) measurements in normal eyes between a rotating Scheimpflug camera combined with a Placido-disk corneal topographer (Sirius, CSO, Italy) and ultrasound pachymetry (USP).

Methods: A systematic literature search was conducted for relevant studies published on PubMed, Medline, EMBASE, and the Cochrane Library and ClinicalTrials.gov from inception to August 1st, 2019. Primary outcome measures were CCT measurements between Sirius and USP. A random effects model was used to pool CCT measurements.

Results: A total of twelve studies involving 862 eyes were included in this meta-analysis. The meta-analysis found CCT measurements between Sirius and USP to be statistically significantly different (P < 0.0001). The mean difference between Sirius and USP was -11.26 μm with a 95% confidence interval (CI) (-16.92 μm, -5.60 μm). The heterogeneity was I² = 60% (P = 0.004).

Conclusion: CCT measurements with the Sirius Scheimpflug-Placido topographer were statistically significantly lower than USP. However, it may be argued that the mean difference of 11.26 μm is not a clinically significant difference.

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Sirius Scheimpflug-Placido与超声厚测法比较中央角膜厚度:meta分析。

背景:比较旋转Scheimpflug相机联合Placido-disk角膜地形仪(Sirius, CSO, Italy)和超声测厚仪(USP)在正常眼睛中角膜中央厚度(CCT)测量的差异。方法:系统检索PubMed、Medline、EMBASE、Cochrane Library和ClinicalTrials.gov网站自成立至2019年8月1日发表的相关研究。主要结果测量是Sirius和USP之间的CCT测量。随机效应模型用于汇总CCT测量值。结果:本荟萃分析共纳入了12项研究，涉及862只眼睛。荟萃分析发现天狼星和USP之间的CCT测量值有统计学意义上的显著差异(P 2 = 60% (P = 0.004))。结论:Sirius Scheimpflug-Placido地形仪的CCT测量值在统计学上显著低于USP。然而，可能有人认为11.26 μm的平均差异在临床上并不具有显著性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Eye and vision (London, England)

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