Could combustion-generated nanoparticles induce cytotoxicity also at the extremely low doses typical of indoor environments?

IF 0.4 Q3 Medicine
Paola Pedata
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引用次数: 0

Abstract

Summary: The presence of nanoparticles in the environment is mainly attributed to outdoor sources but sub-10 nm particles may also form indoor as effect of domestic activities such as cooking, heating, air freshening. Today, due to the COVID-19 pandemic, people are staying home for longer periods of times, thus being exposed to a poor indoor air quality. Due to elevated numerical concentration and large surface area, the health effect of sub-10 nm particles can go beyond what expected from their low mass concentration in the atmosphere. The objective of this study is to find, based on analysis of recent in vitro studies, a dose-effect correlation based on particle size/surface more than on particle mass. Such a correlation cold be useful to assess the health effects of people exposed to very low mass doses of nanoparticles either indoor or outdoor.

燃烧产生的纳米颗粒是否也会在极低的室内环境剂量下引起细胞毒性?
摘要:环境中纳米颗粒的存在主要归因于室外来源,但10纳米以下的颗粒也可能在室内形成,如烹饪、加热、空气清新等家庭活动的影响。今天,由于COVID-19大流行,人们呆在家里的时间更长,因此暴露在较差的室内空气质量中。由于数值浓度升高和表面积大,10纳米以下颗粒对健康的影响可能超出其在大气中的低质量浓度的预期。本研究的目的是根据最近体外研究的分析,发现颗粒大小/表面的剂量效应相关性大于颗粒质量。这种相关性可能有助于评估人们在室内或室外暴露于极低剂量纳米颗粒的健康影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Giornale italiano di medicina del lavoro ed ergonomia
Giornale italiano di medicina del lavoro ed ergonomia PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
CiteScore
0.80
自引率
0.00%
发文量
10
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