Co-expression of Myoepithelial and Melanocytic Features in Carcinoma Ex Pleomorphic Adenoma.

Head and neck pathology Pub Date : 2021-12-01 Epub Date: 2021-02-16 DOI:10.1007/s12105-021-01299-4
Costantino Ricci, Federico Chiarucci, Francesca Ambrosi, Tiziana Balbi, Barbara Corti, Ottavio Piccin, Ernesto Pasquini, Maria Pia Foschini
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引用次数: 2

Abstract

The presence of melanin pigment and melanocytic markers expression have been rarely reported in salivary gland tumors. Herein, two cases of carcinoma arising in pleomorphic adenoma of the parotid gland and showing diffuse expression of myoepithelial and melanocytic markers are described. The clinical-pathological clues useful in the differential diagnosis with melanoma are discussed. In addition, a review of the pertinent literature is also proposed, discussing the pathologic mechanisms potentially involved in this phenomenon.

Abstract Image

Abstract Image

癌性多形性腺瘤中肌上皮和黑素细胞特征的共同表达。
在唾液腺肿瘤中,黑色素和黑色素细胞标记物的表达很少被报道。本文报告两例发生于腮腺多形性腺瘤的癌,表现为肌上皮和黑色素细胞标记物的弥漫性表达。本文讨论了鉴别诊断黑色素瘤的临床病理线索。此外,本文还建议对相关文献进行回顾,讨论可能涉及这一现象的病理机制。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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