Prolonged second stage effect on pelvic floor dysfunction: a follow up survey to a randomized controlled trial.

Alexis C Gimovsky, Jaclyn M Phillips, Molly Amero, Jordan Levine, Vincenzo Berghella
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引用次数: 3

Abstract

Background: Pelvic floor dysfunction is a group of disorders that can significantly impact quality of life due to persistent urinary and anal incontinence. Data evaluating the effect of prolonged second stage of labor and postpartum pelvic floor dysfunction is heterogenous and limited.

Objective: To evaluate whether extending the length of labor in nulliparous women with prolonged second stage affects the presence of self-reported pelvic floor dysfunction after a randomized controlled trial of prolonged second stage.

Study design: We conducted a planned follow up survey to our randomized controlled trial of prolonged second stage of labor using the Pelvic Floor Distress Inventory-20 (PFDI-20). The primary outcome was the PFDI-20 summary score. Secondary outcomes included urinary and fecal incontinence, prolapse, and patient satisfaction. Women surveyed were nulliparous patients with epidural anesthesia, previously enrolled in a randomized controlled trial that assigned them to extended labor, at least 1 additional hour in the second stage if they were undelivered after three hours, or to usual labor, defined as expedited delivery after three hours in the second stage. Women were surveyed at 12 - 36 months postpartum.

Results: Thirty-four of the seventy-eight women responded to the survey (43.6%). 17 women (50.0%) were from the extended labor group and 17 from the usual labor group (50.0%). Maternal demographic data were not significantly different between groups. The PFDI-20 summary score was 13.8 ± 23.3 in the extended labor group and 13.1 ± 20.9 in the usual labor group (p = 0.9). The Pelvic Organ Prolapse Distress Inventory-6 was 1.2 ± 2.9 in the extended labor group and 2.7 ± 6.4 in the usual labor group (p = 0.4). The Colorectal-Anal Distress Inventory-8 was 0.8 ± 2.8 in the extended labor group and 2.1 ± 4.0 in the usual labor group (p = 0.6). The Urinary Distress Inventory-6 was 11.8 ± 21.1 in the extended labor group and 8.3 ± 14.5 in the usual labor group (p = 0.6). Maternal and neonatal outcomes, as well as patient satisfaction, were not statistically significantly different between groups.

Conclusion: Extending the length of labor in nulliparas with singleton gestations, epidural anesthesia, and prolonged second stage did not have an impact on PFDI-20 scores at 12-36 months postpartum. However, our study was underpowered to detect small, but potentially clinically important, differences.

Clinical trial number: NCT02101515 (Study Registration Date March 28, 2014) https://clinicaltrials.gov/ct2/show/NCT02101515.

延长第二阶段对盆底功能障碍的影响:一项随机对照试验的随访调查。
背景:骨盆底功能障碍是一组因持续性尿失禁和肛门失禁而显著影响生活质量的疾病。评估第二产程延长和产后盆底功能障碍的影响的数据是不同的和有限的。目的:通过一项延长第二期的随机对照试验,评估延长产程是否会影响第二期延长的未产妇女自我报告的盆底功能障碍的存在。研究设计:我们使用骨盆底窘迫量表-20 (PFDI-20)对延长第二产程的随机对照试验进行了计划的随访调查。主要终点是PFDI-20总评分。次要结局包括尿失禁、脱垂和患者满意度。接受调查的妇女是硬膜外麻醉的无产患者,之前参加了一项随机对照试验,该试验将她们分配到延长分娩,如果她们在三小时后仍未分娩,则在第二阶段至少增加1小时,或正常分娩,定义为在第二阶段加速分娩三小时后。妇女在产后12 - 36个月接受调查。结果:78名女性中有34名回应了调查(43.6%)。延长产程组17例(50.0%),正常产程组17例(50.0%)。产妇人口统计数据组间无显著差异。延长产程组PFDI-20总分为13.8±23.3分,正常产程组为13.1±20.9分(p = 0.9)。延长产程组盆腔器官脱垂窘迫量表-6为1.2±2.9,顺产组为2.7±6.4 (p = 0.4)。延长产程组结直肠肛肠窘迫指数为0.8±2.8,正常产程组为2.1±4.0 (p = 0.6)。延长产程组尿窘迫指数为11.8±21.1,顺产组为8.3±14.5 (p = 0.6)。产妇和新生儿结局以及患者满意度在两组之间没有统计学上的显著差异。结论:单胎妊娠无产产妇延长产程、硬膜外麻醉、延长产程对产后12 ~ 36个月PFDI-20评分无影响。然而,我们的研究在检测微小但具有潜在临床重要性的差异方面能力不足。临床试验号:NCT02101515(研究注册日期2014年3月28日)https://clinicaltrials.gov/ct2/show/NCT02101515。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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