Toxicology and carcinogenesis studies in Sprague Dawley (Hsd:Sprague Dawley SD) rats exposed to whole-body radio frequency radiation at a frequency (900 MHz) and modulations (GSM and CDMA) used by cell phones.

Q4 Medicine
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引用次数: 0

Abstract

The predominant source of human exposure to radio frequency radiation (RFR) occurs through usage of cellular phone handsets. The Food and Drug Administration nominated cell phone RFR emission for toxicology and carcinogenicity testing in 1999. At that time, animal experiments were deemed crucial because meaningful human exposure health data from epidemiological studies were not available. Male and female Sprague Dawley (Hsd:Sprague Dawley SD) rats were exposed to time-averaged whole-body specific absorption rates of Global System for Mobile Communications (GSM)- or Code Division Multiple Access (CDMA)-modulated cell phone RFR at 900 MHz in utero, during lactation, and after weaning for 28 days or 2 years. Genetic toxicology studies were conducted in rat peripheral blood erythrocytes and leukocytes, brain cells, and liver cells. (Abstract Abridged).

Sprague Dawley(Hsd:Sprague Dawley SD)大鼠暴露于手机使用的频率(900 MHz)和调制方式(GSM 和 CDMA)的全身射频辐射下进行的毒理学和致癌研究。
人类暴露于射频辐射(RFR)的主要来源是使用手机。1999 年,美国食品和药物管理局提名对手机射频辐射进行毒理学和致癌性测试。当时,动物实验被认为是至关重要的,因为没有流行病学研究提供的有意义的人类暴露健康数据。雄性和雌性 Sprague Dawley(Hsd:Sprague Dawley SD)大鼠在子宫内、哺乳期和断奶后 28 天或 2 年内都暴露于全球移动通信系统(GSM)或码分多址(CDMA)调制的 900 MHz 手机射频辐射的时间平均全身特定吸收率中。对大鼠外周血红细胞和白细胞、脑细胞和肝细胞进行了遗传毒理学研究。(摘要有删节)。
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CiteScore
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