Cardiac wall motion abnormalities observed in a patient with transient hyperthyroidism.

Takatoshi Sakaki, Yoshio Fujioka, Takafumi Akagami, Miho Masai, Hiroshi Shimizu, Tsuyoshi Sakoda, Takeshi Tsujino, Mitsumasa Ohyanagi
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引用次数: 23

Abstract

A 74-year-old woman, with a history of hypertension and hyperlipidemia, was admitted to our hospital. She was found to have a sinus tachycardia with ST-segment elevations in leads II, III, (a)V(F), and V(3) through V(6) in electrocardiography, hypokinesis of the left ventricular apex by echocardiography, and normal findings on coronary angiography. Blood analysis revealed an increase in the creatine kinase MB fraction, a significant positive detection in troponin T, and transient elevations in the concentrations of free triiodothyronine, free thyroxine, thyroid globulin antibody, and thyroid peroxidase antibody. Defects in myocardial perfusion and fatty acid metabolism in the apical area were also demonstrated by myocardial scintigraphy. These data suggest that tako-tsubo syndrome or myocardial infarction may be induced in patients with mild and transient hyperthyroidism.

一过性甲亢患者心壁运动异常。
一位74岁的女性,有高血压和高脂血症病史,住进我院。她在心电图上发现窦性心动过速伴导联II、III、(a)、V(F)、V(3)至V(6) st段升高,超声心动图显示左心室心尖运动不足,冠状动脉造影正常。血液分析显示肌酸激酶MB分数增加,肌钙蛋白T检测显著阳性,游离三碘甲状腺原氨酸、游离甲状腺素、甲状腺球蛋白抗体和甲状腺过氧化物酶抗体浓度短暂升高。心肌显像还显示了心肌灌注和根尖区脂肪酸代谢的缺陷。这些数据提示,轻度和短暂性甲亢患者可能诱发tako-tsubo综合征或心肌梗死。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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