Dr. Hervé Fernandez M.D. , Dr. Antoine Watrelot M.D. , Dr. Jean-Dominique Alby M.D. , Dr. Jacques Kadoch M.D. , Dr. Amélie Gervaise M.D. , Dr. Renaud deTayrac M.D. , Dr. René Frydman M.D.
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引用次数: 51
Abstract
Study Objective
To evaluate fertiloscopy ovarian drilling with bipolar energy in women with clomiphene citrate-resistant polycystic ovary syndrome (PCOS).
Design
Prospective study (Canadian Task Force classification II).
Setting
University teaching hospital and private clinic.
Patients
Eighty women with clomiphene citrate-resistant PCOS.
Intervention
Operative transvaginal fertiloscopy with a coaxial bipolar electrode.
Measurements and Main Results
During a mean follow-up of 18.1 months (± 6.4), 73 women (91%) recovered regular and ovulatory cycles. The cumulative pregnancy rate was 60% (44/73) for spontaneous and stimulated cycles, with 39.7% (29/73) imputed to drilling alone. The mean time to conceive was 3.9 months (range 1–11.8). There were eight miscarriages (18%), and no ectopic pregnancies or multiple pregnancy. No complications occurred.
Conclusion
Ovarian drilling by transvaginal fertiloscopy with bipolar electrosurgery appears to be an effective minimally invasive procedure in patients with PCOS resistant to clomiphene citrate.
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