The cause of subchondral bone cysts in osteoarthrosis: a finite element analysis.

Hans D Dürr, Heiner Martin, Christoph Pellengahr, Marcus Schlemmer, Markus Maier, Volkmar Jansson
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引用次数: 94

Abstract

Background: The etiology of subchondral bone cysts in arthrotic joints is unclear.

Materials and methods: We used two-dimensional finite element analysis to evaluate the hypothesis that subchondral bone cysts in the osteoarthrotic hip joint may be the result of microfractures caused by localized cartilage defects or a thinned layer of cartilage. We evaluated the equivalent bone stress (von Mises (VM) stress) in the cancellous bone as an indicator of potential microfractures and further development of cystic lesions.

Results: Cartilage defects induced stress peaks in the subchondral bone. This peak stress distribution corresponded to the clinical observation of development of acetabular and femoral subchondral cysts in a "kissing" position. A femoral subchondral bone cyst induced a stress peak at the corresponding acetabular site, whereas subchondral acetabular cysts did not increase stress in the femoral head. Acetabular cysts showed an increased level of stress at the lateral and medial border of the lesion which was much higher than the stress levels in the femoral head, indicating a tendency to faster growth.

Interpretation: Our study supports the theory that stress-induced bone resorption may cause development of subchondral bone cysts in osteoarthrosis.

骨关节病软骨下骨囊肿的成因:有限元分析。
背景:关节软骨下骨囊肿的病因尚不清楚。材料和方法:我们采用二维有限元分析的方法来评估髋关节软骨下骨囊肿可能是由局部软骨缺损或软骨层变薄引起的微骨折的假设。我们评估了松质骨中的等效骨应力(von Mises (VM)应力)作为潜在微骨折和囊性病变进一步发展的指标。结果:软骨缺损引起软骨下骨应力峰值。这种峰值应力分布与临床观察的“亲吻”体位髋臼和股骨软骨下囊肿的发展相一致。股骨软骨下骨囊肿在相应的髋臼部位引起应力峰值,而软骨下髋臼囊肿不增加股骨头的应力。髋臼囊肿显示病变外侧和内侧边界的应力水平增加,远高于股骨头的应力水平,表明有更快生长的趋势。解释:我们的研究支持应力诱导的骨吸收可能导致骨关节病软骨下骨囊肿发展的理论。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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