{"title":"Coronary dilators and cardioplegia.","authors":"Alexander Romagnoli, Adolph J. Koska","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The distribution in the myocardium of cardioplegic solution is demonstrated in dog hearts with the aid of indocyanine green. When papaverine or nitroglycerin are added to the solution, a much improved diffusion is observed. Papaverine appears to be a better coronary dilator. We deduce from this observation that myocardial protection during ischemic arrest for open-heart surgery is enhanced considerably when coronary dilation is assured.</p>","PeriodicalId":84396,"journal":{"name":"Cardiovascular diseases","volume":"8 4","pages":"467-474"},"PeriodicalIF":0.0000,"publicationDate":"1981-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC287983/pdf/cardiodis00004-0007.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cardiovascular diseases","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract
The distribution in the myocardium of cardioplegic solution is demonstrated in dog hearts with the aid of indocyanine green. When papaverine or nitroglycerin are added to the solution, a much improved diffusion is observed. Papaverine appears to be a better coronary dilator. We deduce from this observation that myocardial protection during ischemic arrest for open-heart surgery is enhanced considerably when coronary dilation is assured.
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