[10 years experience in surgical resuscitation at a university hospital center. Determination of a criterion for identifying patients at risk for fatal irreversible coagulopathy].

N Schreyer, A Engeler, P F Leyvraz
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Abstract

The authors evaluated ten years of surgical reanimation in the University Centre of Lausanne (CHUV). Irreversible coagulopathy (IC) is the predominant cause of death for the polytraumatized patient. Acidosis, hypothermy, and coagulation troubles are crucial elements of this coagulopathy. The authors looked for a criterion allowing the identification of dying of IC. In a retrospective study, laboratory results of pH, TP, PTT, thrombocyte count and the need for blood transfusion units were checked for each major step of the primary evaluation and treatment of the polytraumatized patients. These results were considered as critical according to criteria of the literature (30). The authors conclude that the apparation of a third critical value may be useful to identify the polytraumatized patient at risk of dying of IC status. This criterion may also guide the trauma team in selecting a damage control surgical approach (DCS). This criterion was then introduced into an algorithm involving the Emergency Department, the operating room and the Intensive Care Unit. This criterion is a new tool to address the patient at the crucial moment to the appropriate hospital structure.

在大学医院中心有10年的外科复苏经验。确定致命的不可逆凝血功能障碍危险患者的标准。
作者评估了洛桑大学中心(CHUV)十年的手术复苏情况。不可逆性凝血功能障碍(IC)是多创伤患者死亡的主要原因。酸中毒、体温过低和凝血障碍是这种凝血病的关键因素。作者寻找一种能够识别IC死亡的标准。在一项回顾性研究中,在对多创伤患者进行初步评估和治疗的每个主要步骤中,检查了pH, TP, PTT,血小板计数和输血单位的实验室结果。根据文献的标准,这些结果被认为是关键的(30)。作者得出结论,第三个临界值的出现可能有助于识别有IC状态死亡风险的多重创伤患者。这个标准也可以指导创伤小组选择损伤控制手术入路(DCS)。这一标准随后被引入到涉及急诊科、手术室和重症监护病房的算法中。这个标准是一个新的工具,以解决病人在关键时刻适当的医院结构。
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