Dynamic resource allocation for epidemic control in multiple populations.

Gregory S Zaric, Margaret L Brandeau
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Abstract

We develop a dynamic resource allocation model in which a limited budget for epidemic control is allocated over multiple time periods to interventions that affect multiple populations. For certain special cases with two time periods, multiple independent populations, and a linear relationship between investment in a prevention programme and the resulting change in risky behaviour, we demonstrate that the optimal solution involves investing in each period as much as possible in some of the populations and nothing in all the other populations. We present heuristic algorithms for solving the general problem, and present numerical results. Our computational analyses suggest that good allocations can be made based on some fairly simple heuristics. Our analyses also suggest that allowing for some reallocation of resources over the time horizon of the problem, rather than allocating resources just once at the beginning of the time horizon, can lead to significant increases in health benefits. Allowing for reallocation of funds may generate more health benefits than use of a sophisticated model for one-time allocation of resources.

多种群流行病控制的动态资源分配。
我们开发了一个动态资源分配模型,在该模型中,用于流行病控制的有限预算在多个时间段内分配给影响多个人群的干预措施。对于具有两个时间段、多个独立人群以及在预防计划中的投资与由此产生的风险行为变化之间存在线性关系的某些特殊情况,我们证明了最优解决方案包括在每个时间段对某些人群进行尽可能多的投资,而在所有其他人群中不进行任何投资。我们提出了求解一般问题的启发式算法,并给出了数值结果。我们的计算分析表明,良好的分配可以基于一些相当简单的启发式。我们的分析还表明,允许在问题的时间范围内重新分配资源,而不是在时间范围开始时只分配一次资源,可以显著增加健康效益。允许重新分配资金可能比使用一次性分配资源的复杂模式产生更多的健康效益。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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