[Lymph node excision in invasive Barrett carcinoma].

H J Stein, M Feith, J R Siewert
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Abstract

Similar to squamous cell esophageal cancer, the lymph node status constitutes the major prognostic factor after complete tumor resection (R0-resection) in patients with adenocarcinoma of the distal esophagus (the so-called Barrett's cancer). Lymphatic spread in patients with Barrett's cancer, however, appears to follow certain rules. Lymphatic spread is closely correlated to the pT-category of the primary tumor, starts only after infiltration of the submucosa und is initially limited to the regional lymph nodes. Distant lymph node metastases are almost exclusively found in patients with multiple positive regional nodes, skipping of regional lymph nodes is rare. These observations set the stage for tailored lymphadenectomy-strategies based on the, sentinel-lymphadenectomy' concept.

浸润性巴雷特癌的淋巴结切除。
与食管鳞状细胞癌相似,食管远端腺癌(即Barrett癌)患者的淋巴结状态是其完全肿瘤切除(R0-resection)后的主要预后因素。然而,巴雷特癌患者的淋巴扩散似乎遵循一定的规律。淋巴扩散与原发肿瘤的pt类型密切相关,仅在粘膜下层浸润后才开始,最初局限于局部淋巴结。远端淋巴结转移几乎只发生在多个阳性区域淋巴结的患者中,区域淋巴结的跳跃是罕见的。这些观察结果为基于哨兵淋巴结切除术概念的量身定制的淋巴结切除术策略奠定了基础。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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