Generation of chirality by the aggregation of column structures for two-component molecular crystals composed of chloronitrobenzoic acids and p-anisidine.

Abstract

Four two-component molecular crystals 1.2, 1.3, 1.4 and 1.5 composed of chloronitrobenzoic acids and p-anisidine as components have been prepared. Among these molecular crystals, 1.2 and 1.3 showed the generation of chirality (space group P2(1)) by aggregation of mutually parallel column structures with their 2(1) axes pointing in the same direction, and the others showed no chirality. This paper shows that the generation of chirality in a molecular crystal can be explained on the basis of the aggregation of column structures and that weaker intermolecular interactions affect the generation of chiral molecular crystal.