The Bloom's syndrome helicase: keeping cancer at bay.

Q4 Agricultural and Biological Sciences

Biologist Pub Date : 2003-02-01

Payam Mohaghegh, Ian D Hickson

引用次数: 0

Abstract

Bloom's syndrome, a very rare inherited disorder, predisposes its sufferers to the full range of cancers that afflict humanity. This predisposition is rooted in just one defective gene on chromosome 15. It encodes the BLM helicase - an enzyme that ordinarily protects against DNA damage arising during replication.

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布卢姆氏综合症解旋酶:阻止癌症。

布鲁姆氏综合症是一种非常罕见的遗传性疾病，它使患者容易患上折磨人类的各种癌症。这种倾向仅仅源于15号染色体上的一个缺陷基因。它编码BLM解旋酶——一种通常保护DNA免受复制过程中产生的损伤的酶。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Biologist Agricultural and Biological Sciences-Agricultural and Biological Sciences (all)

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