Management of stage I nonseminomatous germ-cell tumors.

John Thomas, Michael Aleman, Robert Dreicer, Eric A Klein
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引用次数: 6

Abstract

Following orchiectomy in patients with stage 1 nonseminomatous germ-cell tumors (NSGCT), there are three treatment options. Retroperitoneal lymph-node dissection (RPLND) is currently the treatment of choice in the United States and can be both diagnostic and therapeutic but is associated with surgical morbidities. Surveillance is the least invasive but carries the highest potential for relapse and can be timely and costly for both patient and physician. Primary chemotherapy avoids the morbidity of surgery while achieving similar survival rates, albeit with potentially significant side effects. The advantages and disadvantages of each treatment modality are discussed.

I期非半细胞性生殖细胞肿瘤的治疗。
1期非半细胞性生殖细胞肿瘤(NSGCT)患者行睾丸切除术后,有三种治疗选择。腹膜后淋巴结清扫术(RPLND)是目前美国的首选治疗方法,既可诊断也可治疗,但与手术并发症有关。监测是侵入性最小的,但复发的可能性最大,对病人和医生来说都是及时和昂贵的。初级化疗避免了手术的发病率,同时获得了相似的生存率,尽管有潜在的显著副作用。讨论了每种处理方式的优缺点。
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