[Poliomyelitis in Madagascar (1988-1996): current situation in the World Health eradication program by the year 2000].

H G Zeller, M Rakoto-Andrianarivelo, A Andrianaivoarisoa, M M Hacen, B Andriamahezafy, R Osseni, S Randriamesy, D R Rakotoarimanana, N Nazaraly
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Abstract

The number of acute flaccid paralysis (AFP) cases reported to World Health Organization (WHO) decreased from 1988 (48 cases) to 1996 (8 cases), but the real endemic situation of poliomyelitis is unknown. Cases are under or misreported. Very often, notifications are delayed; virological investigations of the etiology could not be performed as well as the environment studies and the immunization ripostes. In 1996, only one AFP case was confirmed by isolation of wild poliovirus. The immunization coverage in children under one by OPV (3 doses) was 73.0% in 1996 from the statistics of the Public Health Services but only 54.7% from randomized studies. The eradication of poliomyelitis by the year 2000 has engaged Madagascar in the disease prevention by improving the immunization coverage within the Expanded Immunization Programme in association with the Organization of National Immunization Days in October and November 1997. Likewise, the Virological Unit of the Pasteur Institute was recognized as the National WHO Reference Centre for Polio.

[马达加斯加的小儿麻痹症(1988-1996年):到2000年消灭世界卫生方案的现状]。
向世界卫生组织(WHO)报告的急性弛缓性麻痹(AFP)病例数从1988年的48例下降到1996年的8例,但脊髓灰质炎的真实流行情况尚不清楚。病例少报或误报。通常情况下,通知会被延迟;病原学的病毒学调查不能像环境研究和免疫应答那样进行。1996年,通过分离野生脊髓灰质炎病毒仅确认了一例AFP病例。根据公共卫生服务的统计,1996年1岁以下儿童口服脊髓灰质炎疫苗(3剂)的免疫接种率为73.0%,但根据随机研究,这一数字仅为54.7%。到2000年消灭小儿麻痹症使马达加斯加参与到疾病预防工作中来,办法是在1997年10月和11月全国免疫日组织的配合下,在扩大免疫方案范围内扩大免疫覆盖面。同样,巴斯德研究所的病毒学单位被公认为世界卫生组织小儿麻痹症国家参考中心。
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