Evidence of saxitoxin derivatives as causative agents in the 1997 mass mortality of monk seals in the Cape Blanc Peninsula.

M Reyero, E Cacho, A Martínez, J Vázquez, A Marina, S Fraga, J M Franco
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引用次数: 59

Abstract

Monk seals in Cape Blanc (Western Sahara coast) suffered a mass mortality during May-July 1997 which was attributed to a morbillivirus. High performance liquid chromatography (HPLC) analysis on tissues of seals killed during the outbreak and on related fauna showed peaks with retention times coincident with those of some saxitoxin derivatives but their identity was not proved. Here we present results of further HPLC analyses that unambiguously prove the identity of these toxins by mass spectrometry (MS), supporting the hypothesis that this mortality of monk seals was caused by biotoxins rather than by a morbillivirus.

1997年勃朗角半岛僧海豹大量死亡的证据表明,蛤蚌毒素衍生物是致病菌。
1997年5月至7月期间,勃朗角(西撒哈拉海岸)僧海豹大量死亡,死因是一种麻疹病毒。对疫情期间死亡的海豹和相关动物的组织进行高效液相色谱分析,发现其停留时间与一些蛤蚌毒素衍生物的停留时间一致,但其身份尚未得到证实。在这里,我们提出了进一步的HPLC分析结果,通过质谱(MS)明确地证明了这些毒素的身份,支持了僧侣海豹的死亡是由生物毒素而不是由麻疹病毒引起的假设。
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