[Nasal CPAP therapy in obstructive sleep apnea syndrome: patient compliance].

W Karrer, T B Rothe, A Ryckx, U Keller
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Abstract

We aimed in 186 patients with obstructive sleep apnoea, consecutively treated with nasal CPAP between January 1990 and December 1997, to evaluate compliance with nCPAP therapy and to explore factors influencing compliance. At 3 to 6 months (K1), 1 to 2 years (K2) and more than 3 years (K3) patients were reexamined regarding clinical conditions, the mean time of nCPAP usage per night, nCPAP pressure, and body mass index (BMI). The regularly conducted controls consisted of checking mask fitting, polygraphy with automatic pressure titration and once, mostly at K1, polysomnography. Compliance with nCPAP was considered to be sufficient more than 4 hours of usage per night. At K1, 9 patients had stopped therapy, 5 had moved away, 6 had changed therapy, 6 had died, and 41 had not been treated long enough to have a follow-up at K1. Thus we were able to reexamine 119 patients with ongoing nCPAP therapy. We found no correlation between indices of severeness of sleep apnoea (apnoea/hypopnea index, mean low of night time oxygen saturation, nCPAP pressure, and BMI) and compliance. At K1 87 patients (73%) had sufficient nCPAP compliance. All of them showed sufficient compliance at K2 and K3 too. We conclude that a sufficient compliance at an initial control implies sufficient compliance later on. 32 patients (27%) showed insufficient compliance at K1. Of this group 41% (13 patients) improved compliance at K2. This result underlines the value of a second instruction in nCPAP therapy when patient compliance was lacking initially.

[鼻腔CPAP治疗阻塞性睡眠呼吸暂停综合征:患者依从性]。
本研究以1990年1月至1997年12月期间连续接受鼻腔CPAP治疗的186例阻塞性睡眠呼吸暂停患者为研究对象,评价其依从性并探讨影响依从性的因素。在3至6个月(K1)、1至2年(K2)和3年以上(K3)时,对患者的临床状况、每晚平均使用nCPAP的时间、nCPAP压力和体重指数(BMI)进行复查。定期进行的控制包括检查口罩贴合,自动压力滴定测谎,以及一次(主要在K1时)多导睡眠图。遵守nCPAP被认为足以每晚使用超过4小时。在K1, 9名患者停止治疗,5名患者转移,6名患者改变治疗,6名患者死亡,41名患者治疗时间不够长,无法在K1进行随访。因此,我们能够重新检查119例正在进行nCPAP治疗的患者。我们发现睡眠呼吸暂停严重程度指数(呼吸暂停/低通气指数、夜间平均低氧饱和度、nCPAP压和BMI)与依从性之间没有相关性。在K1时,87例患者(73%)有足够的nCPAP依从性。它们在K2和K3处也表现出充分的顺应性。我们得出结论,在初始控制时的充分遵从意味着以后的充分遵从。32例(27%)患者K1依从性不足。在该组中,41%(13例)患者的K2依从性得到改善。这一结果强调了当患者最初缺乏依从性时,在nCPAP治疗中进行第二次指导的价值。
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