Comparison of FDG-PET and Bone Scans for Detecting Skeletal Metastases in Patients with Non-small Cell Lung Cancer

Jolanta M Durski MD , Sandhya Srinivas MD , George Segall MD
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引用次数: 19

Abstract

Purpose: Positron Emission Tomography (PET) with F18-fluorodeoxyglucose has been proven useful for staging non-small cell lung cancer. Bone scans are frequently performed for suspected skeletal metastases. The purpose of this study was to evaluate if bone scans compared to PET scans provide additional information that changes the stage of disease.

Procedures: Nineteen patients with non-small cell lung cancer had PET and bone scans done for staging of the malignancy. The results of both studies were compared.

Results: Bone and PET scans agreed on the presence or absence of skeletal metastases in all nineteen patients. The addition of a bone scan to a PET scan did not change the stage of the disease or the management in any of the patients. Bone scans allowed for more precise localization of the lesions in some patients.

Conclusions: Bone scans do not change the stage of disease when performed in addition to PET scans, but provide more precise localization of skeletal abnormalities.

FDG-PET与骨扫描检测非小细胞肺癌骨转移的比较
目的:f18 -氟脱氧葡萄糖正电子发射断层扫描(PET)已被证明对非小细胞肺癌的分期有用。骨扫描常用于疑似骨骼转移。本研究的目的是评估骨扫描与PET扫描相比是否提供了改变疾病分期的额外信息。方法:19例非小细胞肺癌患者进行了PET和骨扫描,以确定恶性肿瘤的分期。对两项研究的结果进行了比较。结果:骨和PET扫描一致的存在或不存在骨骼转移在所有19例患者。在PET扫描的基础上增加骨骼扫描并没有改变任何患者的疾病阶段或治疗方法。骨扫描可以更精确地定位某些患者的病变。结论:在PET扫描的基础上进行骨扫描不会改变疾病的分期,但可以更精确地定位骨骼异常。
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