Developing Techniques and Strategies for the Management of Cancer Pain.

Burgess, Haworth
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引用次数: 3

Abstract

The past 20 years have seen a great surge of interest in understanding and treating pain. The introduction of sustained-release opioid delivery systems has tremendously advanced our ability to provide improved pain control. Parenteral opioid delivery systems, although available in many developed nations, remain expensive and cumbersome. New advances in parenteral sustained-release systems are currently in development. These advances include liposomal opioid preparations for intrathecal use, transcutaneous patient-controlled delivery, and implantable diffusion reservoirs. Even more exciting are new developments in tissue engineering that may allow the transplantation of human or animal cells, capable of producing natural analgesic substances, into the vicinity of the spinal cord.

发展癌症疼痛管理的技术和策略。
在过去的20年里,人们对理解和治疗疼痛的兴趣激增。阿片类药物缓释系统的引入极大地提高了我们改善疼痛控制的能力。尽管在许多发达国家都有阿片类药物注射系统,但仍然昂贵且笨重。目前正在开发肠外缓释系统的新进展。这些进展包括用于鞘内使用的阿片脂质体制剂,经皮患者控制给药,以及植入式弥散储存器。更令人兴奋的是组织工程方面的新进展,它可能允许将能够产生天然镇痛物质的人类或动物细胞移植到脊髓附近。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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