Pulsatile tinnitus in patients with morbid obesity: the effectiveness of weight reduction surgery.

The American journal of otology Pub Date : 2000-09-01
E M Michaelides, A Sismanis, H J Sugerman, W L Felton
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Abstract

Background: Morbid obesity is increasing in the United States population. Morbidly obese patients may have disabling pulsatile tinnitus (PT) secondary to pseudotumor cerebri syndrome and often seek treatment from otolaryngologists because of this symptom.

Objective: To determine the effectiveness of weight reduction surgery (WRS) for relief of PT in patients with morbid obesity.

Study design: Retrospective study of morbidly obese patients with associated PT.

Setting: Academic tertiary referral center.

Patients: Sixteen women with morbid obesity and associated PT who underwent WRS.

Results: Median age was 34 years (range 24-45 years). Average preoperative body mass index was 45 kg/m2 (range 33-70 kg/m2). Average weight loss was 45+/-17 kg (range 25-99 kg). Average postoperative weight was 75+/-14 kg (range 57-105 kg). The average preoperative cerebrospinal fluid pressure was 344+/-103 mm H2O (range 220-520 mm H2O). Postoperative measurements of cerebrospinal fluid, obtained on 4 patients, revealed an average decrease in pressure of 198 mm H2O (range 120-400 mm H2O). Thirteen patients experienced complete resolution of their PT (81%). Three patients continued to have PT despite significant weight reduction.

Conclusions: Weight reduction surgery was effective in relieving PT in morbidly obese patients with associated pseudotumor cerebri syndrome and should be considered when conservative management has failed.

病态肥胖患者搏动性耳鸣:减重手术的有效性。
背景:病态肥胖在美国人口中呈上升趋势。病态肥胖患者可能有继发于假性脑瘤综合征的致残性脉动性耳鸣(PT),并且经常因为这种症状寻求耳鼻喉科医生的治疗。目的:探讨减重手术(WRS)缓解病态肥胖患者PT的效果。研究设计:回顾性研究的病态肥胖患者与相关的pt。设置:学术三级转诊中心。患者:16名患有病态肥胖和相关PT的女性接受了WRS。结果:中位年龄34岁(范围24-45岁)。术前平均体重指数为45 kg/m2(范围33 ~ 70 kg/m2)。平均体重减轻45+/-17 kg(范围25-99 kg)。术后平均体重75+/-14 kg(范围57-105 kg)。术前平均脑脊液压为344±103 mm H2O(范围220 ~ 520 mm H2O)。4例患者术后脑脊液测量显示,平均压力下降198 mm H2O(范围120-400 mm H2O)。13例患者PT完全消退(81%)。三名患者尽管体重明显减轻,但仍继续接受PT治疗。结论:减重手术可有效缓解伴有假性脑肿瘤综合征的病态肥胖患者的PT,当保守治疗失败时应考虑减重手术。
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