Immune recognition of glomerular antigens.

R G Phelps
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引用次数: 4

Abstract

Autoimmunity is thought to cause most varieties of glomerulonephritis including membranous nephropathy, minimal-change nephropathy, Goodpasture's disease and possibly IgA nephropathy. Much effort has been and is directed at understanding the mechanisms of immune system driven inflammation and of the consequent renal injury and repair or scarring. The purpose of this article is to focus attention on the way the immune system recognizes kidney autoantigens, a process that must be a pivotal in the initiation of autoimmune kidney disease.

肾小球抗原的免疫识别。
自身免疫被认为是大多数肾小球肾炎的病因,包括膜性肾病、微小改变肾病、good牧草病和可能的IgA肾病。很多的努力都是为了理解免疫系统驱动的炎症以及随之而来的肾损伤和修复或瘢痕形成的机制。本文的目的是关注免疫系统识别肾脏自身抗原的方式,这一过程在自身免疫性肾脏疾病的发生中必须是关键的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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