Squamous cell carcinoma of the external auditory canal: an evaluation of a staging system.

The American journal of otology Pub Date : 2000-07-01
S A Moody, B E Hirsch, E N Myers
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Abstract

Objective: The study was conducted to review a staging system proposed by the University of Pittsburgh for temporal bone cancer and to evaluate survival status according to stage, treatment, and certain prognostic factors.

Study design: The study was a retrospective case review.

Setting: The study was conducted at a tertiary care medical center and specialty hospital.

Patients: Thirty-two patients with primary squamous cell carcinoma of the external auditory canal were studied.

Intervention: All patients underwent surgery of the temporal bone. Radiotherapy was given depending on tumor stage and histopathologic findings.

Main outcome measures: The 2-year survival rates of patients undergoing surgical resection with or without adjuvant radiotherapy.

Results: The 2-year survival rates for primary squamous cell carcinoma of the temporal bone were as follows: T1 lesions 100%, T2 80%, T3 50%, and T4 7%. Survival for T3 tumors was 75% with postoperative radiotherapy, compared with 0% with surgery alone.

Conclusions: The 2-year survival data directly correlated with the staging system. The use of adjuvant radiotherapy increased survival rate in patients with a T3 lesion.

外耳道鳞状细胞癌:分期系统的评估。
目的:本研究回顾了匹兹堡大学提出的颞骨癌分期系统,并根据分期、治疗和某些预后因素评估患者的生存状况。研究设计:本研究为回顾性病例回顾。环境:研究在三级医疗中心和专科医院进行。患者:对32例外耳道原发性鳞状细胞癌进行了研究。干预:所有患者均行颞骨手术。根据肿瘤分期及组织病理表现给予放疗。主要观察指标:手术切除患者伴或不伴辅助放疗的2年生存率。结果:原发性颞骨鳞状细胞癌2年生存率T1为100%,T2为80%,T3为50%,T4为7%。T3肿瘤术后放疗的生存率为75%,而单纯手术的生存率为0%。结论:2年生存数据与分期系统直接相关。辅助放疗的使用提高了T3病变患者的生存率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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