Functional domains, structural variations and pathogen interactions of MCP, DAF and CR1.

D Hourcade, M K Liszewski, M Krych-Goldberg, J P Atkinson
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引用次数: 92

Abstract

The Regulators of Complement Activation (RCA) are a fascinating group of proteins that play important roles in innate and acquired immunity. In this review, we examine structure-function aspects of three membrane-bound RCA proteins and discuss the unique impact of their genetic organization on their evolution.

MCP、DAF和CR1的功能域、结构变异和病原体相互作用。
补体激活调节因子(regulatory of Complement Activation, RCA)是一组在先天免疫和获得性免疫中起重要作用的蛋白质。在这篇综述中,我们研究了三种膜结合RCA蛋白的结构和功能方面,并讨论了它们的遗传组织对它们进化的独特影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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