J A García-Erce, A Seoane, V M Solano, C Salvador Osuna, A Pérez-Layo, E Gómez-Arteta, J J Gimeno
{"title":"[Anti-A antibodies and bacterial contamination of platelet concentrates].","authors":"J A García-Erce, A Seoane, V M Solano, C Salvador Osuna, A Pérez-Layo, E Gómez-Arteta, J J Gimeno","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>The possible ABO group antibodies protective function against several infections has been classically described. We analyze the platelet concentrates (PC) bacterial control results and their ABO antibodies.</p><p><strong>Material and methods: </strong>We studied 245 outdated PCs (> 5 days). The samples were sterilely collected for adequate microbiological investigation studies on sheep-blood agar plates. If bacterial growth is found, the microbiological identification is performed on the basis of standard tests, the specific anti-biotype being achieved by disk-diffusion method on Müeller-Hinton agar plates, and the red cell concentrate was analyzed.</p><p><strong>Results: </strong>Bacterial growth by negative coagulase Staphylococcus was found in 10 PCs (4.1%; CI95%; 1.97-7.37). The contaminated PCs lacked natural anti-A antibodies. There were no statistical differences when we analyzed the PC's age, colour or blood group.</p><p><strong>Comments: </strong>The anti-A antibodies may be a protective factor versus PCs contamination caused by resident bacteria.</p>","PeriodicalId":76513,"journal":{"name":"Sangre","volume":"44 6","pages":"434-7"},"PeriodicalIF":0.0000,"publicationDate":"1999-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Sangre","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Objectives: The possible ABO group antibodies protective function against several infections has been classically described. We analyze the platelet concentrates (PC) bacterial control results and their ABO antibodies.
Material and methods: We studied 245 outdated PCs (> 5 days). The samples were sterilely collected for adequate microbiological investigation studies on sheep-blood agar plates. If bacterial growth is found, the microbiological identification is performed on the basis of standard tests, the specific anti-biotype being achieved by disk-diffusion method on Müeller-Hinton agar plates, and the red cell concentrate was analyzed.
Results: Bacterial growth by negative coagulase Staphylococcus was found in 10 PCs (4.1%; CI95%; 1.97-7.37). The contaminated PCs lacked natural anti-A antibodies. There were no statistical differences when we analyzed the PC's age, colour or blood group.
Comments: The anti-A antibodies may be a protective factor versus PCs contamination caused by resident bacteria.
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