The Emory Angioplasty vs Surgery Trial (EAST).

S B King
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引用次数: 12

Abstract

The Emory Angioplasty vs Surgery Trial (EAST) was the outgrowth of the vision of Andreas Grüntzig, expressed as early as 1983, to compare the two revascularization methods in patients with multivessel disease. With sponsorship of the National Heart, Lung and Blood Institute, 392 patients were randomized and followed with 1- and 3-year angiograms and perfusion nuclear scans, and 450 patients were followed in a parallel registry starting in 1987. Now with complete 8-year follow-up, there is no significant survival difference. Revascularization was more complete in the surgery patients, and repeat procedures more common in the PTCA group. Excess procedures in follow-up were concentrated in the first years and the extended 5-year follow-up showed relatively equal use of repeat procedures. The superiority of surgery in diabetic patients seen in the BARI trial was also supported by the EAST findings.

Emory血管成形术与外科手术试验(EAST)。
Emory血管成形术与外科手术试验(EAST)是Andreas grntzig早在1983年就提出的愿景的产物,目的是比较多血管疾病患者的两种血运重建方法。在国家心脏、肺和血液研究所的赞助下,392名患者随机接受了1年和3年的血管造影和灌注核扫描,450名患者在1987年开始的平行登记中接受了随访。随访8年,两组生存率无明显差异。手术患者的血运重建更完整,PTCA组的重复手术更常见。随访中过多的手术集中在第一年,延长的5年随访显示重复手术的使用相对平等。在BARI试验中看到的手术治疗糖尿病患者的优越性也得到了EAST研究结果的支持。
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