{"title":"Predicting the time needed to achieve steady state if absorption and elimination constants are equal.","authors":"J Singer, L Vereczkey","doi":"10.1023/a:1020947130038","DOIUrl":null,"url":null,"abstract":"<p><p>A simple table is derived to facilitate the rapid estimation of the number of dose administrations needed to achieve a certain fraction of the steady-state plasma concentration in the case of one-compartment model with uniform multiple oral dosing and equal absorption and elimination constants.</p>","PeriodicalId":16765,"journal":{"name":"Journal of Pharmacokinetics and Biopharmaceutics","volume":"27 3","pages":"297-300"},"PeriodicalIF":0.0000,"publicationDate":"1999-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/a:1020947130038","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Pharmacokinetics and Biopharmaceutics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1023/a:1020947130038","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
A simple table is derived to facilitate the rapid estimation of the number of dose administrations needed to achieve a certain fraction of the steady-state plasma concentration in the case of one-compartment model with uniform multiple oral dosing and equal absorption and elimination constants.