Hemorheological profile in chronic venous insufficiency after surgery.

Haemostasis Pub Date : 1999-01-01 DOI:10.1159/000022505
G Azaceta, S Romero, J A Moreno, A Vaquerizo, T Olave, C Lorente, J M Azcona, M Gutiérrez
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引用次数: 2

Abstract

In recent years, there have been rheological abnormalities reported in chronic venous insufficiency (CVI), mainly an increase of erythrocyte aggregability (EA), which probably take part in the pathophysiology of the disease. The aim of this study was to analyze the hemorheological profile after stripping in 45 patients suffering from CVI. Follow-up included laboratory tests on the 7th, 60th and 180th day after surgery. EA was assessed with a photometric aggregometer (MA1, Myrenne) in stasis and low shear (3 s(-1)). The results show an increase of EA on the 7th day after surgery (p<0.001). Two and 6 months later, EA values returned to those found prior to surgery. The plasma fibrinogen level changes in a way parallel to EA. The association between rheological disturbances and thrombogenesis is well known, so the hyperaggregability found supports the antithrombotic prophylaxis in the early postsurgical period. On the other hand, the hemorheological abnormalities persist after stripping, so postsurgical treatment to inhibit EA may be beneficial.

手术后慢性静脉功能不全的血液流变学特征。
近年来,慢性静脉功能不全(chronic venous dysfunction, CVI)出现流变学异常,主要表现为红细胞聚集性(erythrocyte aggregability, EA)增高,可能参与了该病的病理生理过程。本研究的目的是分析45例CVI患者剥离后的血液流变学特征。随访包括术后第7天、第60天和第180天的实验室检查。在静态和低剪切(3 s(-1))下,用光度聚集仪(MA1, Myrenne)评估EA。结果显示,术后第7天EA升高(p
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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