[The influence of different concentrations of hydrofluoric acid on blood calcium level in rats].

Zhonghua zheng xing shao shang wai ke za zhi = Zhonghua zheng xing shao shang waikf [i.e. waike] zazhi = Chinese journal of plastic surgery and burns Pub Date : 1998-07-01

D Wang, Y Yang, Y Chen

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Abstract

Objective: To evaluate the effects of different concentration of hydrofluoric acid (HF) on local skin and calcium level of serum.

Methods: SD rats were divided into two groups which were wounded by 20% and 40% percent of HF respectively. Samples of blood and wound tissue were harvested at different postburn time for the analysis of the calcium level of the serum and histological study.

Results: It was found that twenty percent of HF was enough to cause a skin damage, and might bring about fatal hypocalcemia after a prolonged contact. High concentration of HF (40%) could cause deep tissue necrosis within a short time, and result in a fatal hypocalcemia within 24 hour even in the case of a small area injury.

Conclusion: It is important to treat the patient with HF injury as early as possible. Sufficient calcium must be applied guided by laboratory study in order to prevent the fatal hypocalcemia.

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[不同浓度氢氟酸对大鼠血钙水平的影响]。

目的:探讨不同浓度氢氟酸(HF)对局部皮肤及血清钙水平的影响。方法:将SD大鼠分为两组，分别用20%和40%的HF损伤。在不同的烧伤后时间采集血液和伤口组织样本，分析血清钙水平和组织学研究。结果:20%的氟化氢足以引起皮肤损伤，长期接触可导致致命的低钙血症。高浓度的HF(40%)可在短时间内引起深部组织坏死，即使是小面积损伤，也可在24小时内导致致命的低钙血症。结论:心衰损伤患者应尽早治疗。为了预防致命的低钙血症，必须在实验室研究的指导下给予足够的钙。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Zhonghua zheng xing shao shang wai ke za zhi = Zhonghua zheng xing shao shang waikf [i.e. waike] zazhi = Chinese journal of plastic surgery and burns

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