Lessons from gene modified mice.

Forum (Genoa, Italy) Pub Date : 1999-10-01
S Lira
{"title":"Lessons from gene modified mice.","authors":"S Lira","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Chemokines have been implicated in leukocyte trafficking, angiogenesis, immunoregulation and development. Understanding these and other chemokine functions in vivo is an enormously complex task, but one that is being facilitated by the application of powerful genetic techniques. Here I will summarise the results of a variety of genetic studies in mice and discuss how they have helped us to understand the biological role of chemokines and their receptors.</p>","PeriodicalId":79489,"journal":{"name":"Forum (Genoa, Italy)","volume":"9 4","pages":"286-98"},"PeriodicalIF":0.0000,"publicationDate":"1999-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Forum (Genoa, Italy)","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

Chemokines have been implicated in leukocyte trafficking, angiogenesis, immunoregulation and development. Understanding these and other chemokine functions in vivo is an enormously complex task, but one that is being facilitated by the application of powerful genetic techniques. Here I will summarise the results of a variety of genetic studies in mice and discuss how they have helped us to understand the biological role of chemokines and their receptors.

基因改造小鼠的经验教训。
趋化因子与白细胞运输、血管生成、免疫调节和发育有关。了解这些和其他趋化因子在体内的功能是一项非常复杂的任务,但强大的遗传技术的应用正在促进这一任务。在这里,我将总结各种小鼠遗传研究的结果,并讨论它们如何帮助我们理解趋化因子及其受体的生物学作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信