Recovery from hepatitis C virus-positive cryoglobulinaemic glomerulonephritis after interferon therapy.

C Mazzaro, A Faelli, S Baracetti, L Mezzoran, E Pussini, F Zorat, G Pozzato
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Abstract

The association between mixed cryoglobulinaemia and chronic hepatitis C virus infection has recently been described. Cryoglobulinaemic glomerulonephritis, a complication of mixed cryoglobulinaemia, is usually treated with immunosuppressive therapy, but, given the presence of viral infection, this therapy is no longer recommended. This report concerns a case of a 30-year-old patient with cryoglobulinaemic glomerulonephritis, refractory to steroid treatment, in whom recovery from hepatitis C virus infection was obtained as well as from cryoglobulinaemic glomerulonephritis after interferon therapy. The clinical symptoms and laboratory tests were normal after prolonged interferon therapy and, 3 years after the end of treatment, the patient is free from disease.

丙型肝炎病毒阳性冷球蛋白血症性肾小球肾炎干扰素治疗后的恢复情况。
混合冷球蛋白血症和慢性丙型肝炎病毒感染之间的关系最近被描述。冷球蛋白血症性肾小球肾炎是混合性冷球蛋白血症的一种并发症,通常采用免疫抑制疗法治疗,但鉴于病毒感染的存在,这种疗法不再被推荐。本报告涉及一例30岁的冷球蛋白血症性肾小球肾炎患者,类固醇治疗难治性,丙型肝炎病毒感染和干扰素治疗后冷球蛋白血症性肾小球肾炎均恢复。长期干扰素治疗后,临床症状和实验室检查正常,治疗结束3年后,患者无疾病。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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