Oxygen uptake efficiency slope as a useful measure of cardiorespiratory functional reserve in adult cardiac patients.

R Baba, K Tsuyuki, Y Kimura, K Ninomiya, M Aihara, K Ebine, N Tauchi, K Nishibata, M Nagashima
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引用次数: 76

Abstract

In this study we aimed to elucidate the validity and usefulness of the oxygen uptake efficiency slope (OUES) in the evaluation of adult cardiac patients. Cardiopulmonary exercise tests were performed on a treadmill by 50 adult patients with chronic heart failure. The OUES was calculated from data for the first 75%, 90%, and 100% of exercise duration. The OUES is derived from the following equation: VO(2)=ax logV(E)+b, where VO(2) is oxygen uptake (ml/kg/min), V(E) is minute ventilation (l/kg/min), and the constant "a" represents OUES. We also determined the ventilatory anaerobic threshold (VAT). The correlation coefficient of the logarithmic curve-fitting model was [mean (SD)] 0.986 (0.009). The OUES could be used to discriminate effectively between New York Heart Association functional classes (P < 0.001). OUES and maximum VO(2) were significantly correlated (r=0.78, P < 0.01). Agreement between the OUES values for the first 90%, 75%, and 100% of the exercise was excellent (intraclass correlation coefficient = 0.99). Our results suggest that OUES is applicable to adult cardiac patients as an objective, effort-independent estimation of cardiorespiratory functional reserve.

摄氧效率斜率作为衡量成人心脏病患者心肺功能储备的有用指标。
在这项研究中,我们旨在阐明氧摄取效率斜率(OUES)在评估成人心脏病患者中的有效性和实用性。本文对50例成年慢性心力衰竭患者在跑步机上进行了心肺运动试验。OUES是根据运动时间的前75%、90%和100%的数据计算的。OUES的推导公式为:VO(2)=ax logV(E)+b,其中VO(2)为摄氧量(ml/kg/min), V(E)为分钟通气量(l/kg/min),常数“a”表示OUES。我们还测定了通气无氧阈值(VAT)。对数曲线拟合模型的相关系数为[mean (SD)] 0.986(0.009)。OUES可用于有效区分纽约心脏协会功能等级(P < 0.001)。OUES与最大VO(2)极显著相关(r=0.78, P < 0.01)。锻炼前90%、75%和100%的OUES值之间的一致性很好(类内相关系数= 0.99)。我们的研究结果表明,OUES作为一种客观的、不依赖于努力的心肺功能储备估计,适用于成年心脏病患者。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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