Synthesis and biophysical studies of modified oligonucleotides containing acyclic amino alcohol nucleoside analogs.

K S Ramasamy, V Stoisavljevic
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引用次数: 3

Abstract

Novel serine derivative of thymine was prepared and incorporated into oligonucleotides. These modified oligonucleotides were studied for their binding affinity with complementary DNA/RNA.

含无环氨基醇核苷类似物修饰寡核苷酸的合成及生物物理研究。
制备了新型胸腺嘧啶丝氨酸衍生物,并将其整合到寡核苷酸中。研究了这些修饰的寡核苷酸与互补DNA/RNA的结合亲和力。
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