[Role of Ca ions and protein kinase C in the action of vitamin E on respiratory burst of neutrophils and blast transformation of lymphocytes].

A A Kapralov
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Abstract

It was shown that vitamin E decreased the stimulating role of oxidative burst activators which influenced on Ca(2+)-dependent mechanisms (A23187, verapamil, FMLP). Jointly addition of this vitamin and blood plasma contained tocopherol-binding proteins influenced on mechanisms associated with protein kinase C. It was shown that Ca ions can also take part in tocopherol's action on blast transformation of lymphocytes.

[钙离子和蛋白激酶C在维生素E对中性粒细胞呼吸爆发和淋巴细胞成细胞转化作用中的作用]。
结果表明,维生素E降低了氧化破裂激活剂的刺激作用,影响Ca(2+)依赖机制(A23187,维拉帕米,FMLP)。该维生素与血浆中含有的生育酚结合蛋白的联合添加影响了蛋白激酶c的相关机制。研究表明,钙离子也可以参与生育酚对淋巴细胞成细胞转化的作用。
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